Let's talk about something interesting about Parkinson's

PARKINSON

Disease (or bad) of Parkinson's is a neurodegenerative disease caused by loss of neurons typically in the substantia nigra and other brain areas. The involvement of this structure causes the appearance of typical symptoms of the disease. Itself is a disorder, usually elderly people, characterized by bradykinesia (slowness of voluntary movements), akinesia (no movement), muscle stiffness and tremor.

The disease was described and documented in 1817 (Essay on the Shaking Palsy) by the British physician Dr. James Parkinson, the associated biochemical changes were identified in the 1960's.

In the early 1960's, the researchers identified a fundamental brain defect that is the hallmark of the disease: loss of brain cells that produce a neurotransmitter - dopamine - fundamental, among others, in the brain circuits involved in controlling movement. This discovery led the scientists to find the first effective treatment for Parkinson's disease and suggested ways to develop new therapies and more effective.

Symptoms

Muscle stiffness.

Tremor can be of different intensities.

Hypokinesia (lack of movement).

Walking difficulties, it seems to follow themselves.

Poor stability when standing, seems to oscillate.

As you begin to have problems walking, have a hard start.

If a move is not finished having difficulty restarting, or to terminate it.

Fish or face mask, for lack of expression of the muscles of the face.

Slowness of movement (bradykinesia).

Akathisia is said of a lack of ability to sit still.

Movement of the fingers as if they were counting money.

Open mouth with difficulty to keep it closed.

Low-pitched voice and monotonous.

Difficulty writing, eating or fine movements.

Intellectual impairment, sometimes.

Constipation.

Depression, anxiety, muscle atrophy.

Treatment

It is difficult to make an accurate diagnosis. Your doctor will ask about your medical history and examine you. Will look for physical signs of tremor, muscle rigidity and slow movements that characterize Parkinson's disease. There are no tests that can confirm the diagnosis. However, sometimes tests are done to confirm that they have no other type of disease. Still can not cure Parkinson's disease. However, there are some medications that can relieve the symptoms greatly.

In mild cases of Parkinson's disease, your doctor may not prescribe medication to prevent side effects that may occur. Your doctor will want to regularly review your symptoms and determine when it would be beneficial to treat it with medication.

The doctor may prescribe medicine to restore the brain's chemical balance. The main goal of treatment is to keep your movements as normal as possible with the least amount of medication. It may not be able to eliminate all your symptoms. Your treatment may include speech therapy and physiotherapy. In severe cases that can not be controlled with medication, you may need surgery to prevent uncontrollable tremors.

Drug

Several different drugs are used to treat Parkinson's disease. Your doctor will try to use the lowest effective dosage to reduce the possibility of occurrence of unwanted side effects.

The main medicine used to treat Parkinson's disease is levodopa. The brain can make dopamine with levodopa. Possible side effects this drug can produce are: abnormal movements of the face, trunk, arms and legs, nausea and vomiting

loss of short-term memory and / or confusion.

Levodopa may work better if you eat less protein. However, do not start a low-protein diet without first talking to your doctor. One of the major risks of a low protein diet is weight loss and malnutrition. If you have narrow angle glaucoma should not take levodopa.

Other medications that your doctor can prescribe are: dopamine-like drugs such as bromocriptine (bromocriptine) and pergolide, amantadine (amantadine), a drug used to treat flu, anticholinergic drugs such as benztropine (Cogentin), trihexyphenidyl ( trihexyphenidil, Artanto) and orphenadrine (Norflex), selegiline (selegiline), a drug that slows the breakdown of dopamine and may help slow the worsening of symptoms as time passes, especially in the initial stages of the disease.

The goal of medicine is trying to restore balance. One form of treatment is Levodopa, which is converted into dopamine in the brain, thereby correcting the imbalance and symptoms are controlled. Another form of treatment is the administration of medications that decrease the effects of acetylcholine. Agonist drugs that increase the action of dopamine are bromocriptine or Parlodel.

Blockers are drugs that block dopamine destruction, decrease the need for large amounts of dopamine and decrease the effects secuendarios ie delay the disease process such as selegiline.

Lately it has been used vitamins C and E are antioxidants weak, prevent the production and accumulation of substances intracerebral product of catabolism of dopamine and substance Call Ringtone free radicals are partly responsible for the worsening of the disease and some side effects.

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All information you provide is general in nature, remember that this information alone can not replace health care or human services you may need. Just provide an information and reference, please consult the health professional who deals with any concerns about your own health.